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KMID : 1044520220850040320
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Tuberculosis and Respiratory Diseases
2022 Volume.85 No. 4 p.320 ~ p.331
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Post-Coronavirus Disease 2019 Pulmonary Fibrosis: Wait or Needs Intervention
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Yoon Hee-Young
Uh Soo-Taek
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Abstract
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Coronavirus disease 2019 (COVID-19) has become a major health burden worldwide, with over 450 million confirmed cases and 6 million deaths. Although the acute phase of COVID-19 management has been established, there is still a long way to go to evaluate the long-term clinical course or manage complications due to the relatively short outbreak of the virus. Pulmonary fibrosis is one of the most common respiratory complications associated with COVID-19. Scarring throughout the lungs after viral or bacterial pulmonary infection have been commonly observed, but the prevalence of post- COVID-19 pulmonary fibrosis is rapidly increasing. However, there is limited information available about post-COVID-19 pulmonary fibrosis, and there is also a lack of consensus on what condition should be defined as post-COVID-19 pulmonary fibrosis. During a relatively short follow-up period of approximately 1 year, lesions considered related to pulmonary fibrosis often showed gradual improvement; therefore, it is questionable at what time point fibrosis should be evaluated. In this review, we investigated the epidemiology, risk factors, pathogenesis, and management of post-COVID-19 pulmonary fibrosis.
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KEYWORD
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Coronavirus Disease 2019, Pulmonary Fibrosis, Complications, Incidence, Pathogenesis, Prognosis, Treatment
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